Worried about your Heart & Kidney Function?
Explore Possible Treatment Options for Heart Failure with Kidney Failure in Texas!
The heart and kidneys are the two most important organs of the body. They work together to keep you healthy. If one stops working as it should, it can cause problems for the other. When you have heart failure (HF) your kidneys can become damaged because the heart cannot pump enough blood and oxygen to them. Similarly, if the kidneys are not working as they should the heart needs to work even harder to get more blood and oxygen to them. This can make HF worse.
When both the heart and kidneys are not functioning properly, the condition is sometimes referred to as cardiorenal syndrome. This dual dysfunction can lead to fluid buildup, fatigue, shortness of breath, and poor appetite, making daily life increasingly difficult. It’s a progressive cycle, where damage to one organ can accelerate the decline of the other.
If you or someone you know is suffering from heart failure and reduced kidney function, Revival Research Institute is conducting Heart Failure with Kidney Failure Clinical Trials, investigating potential new treatment options.
Is this Clinical Trial the Right Fit for You?
To qualify for the Heart Failure with Kidney Failure Clinical Trials, participants must:
- Be 18 years or older
- Diagnosed with symptomatic heart failure
- Have a decline in kidney function
*Additional criteria may apply.
Participation in the Heart Failure with Kidney Failure Clinical Trials is free of cost. To learn more or enroll, fill out the form below, and someone from our research team will contact you to discuss your potential eligibility for the study.
About Heart Failure with Kidney Failure Clinical Trials
Living with chronic heart failure and reduced kidney function can be incredibly tough. It is estimated that in the US people with stage 4 and 5 chronic kidney disease are at increased risk of heart failure.
Revival Research Institute is conducting a clinical trial to evaluate the safety and effectiveness of an investigational treatment for adults diagnosed with chronic heart failure and reduced kidney function. The study aims to explore whether this treatment can help people manage complications in their condition.
The trial is being conducted at multiple sites across the United States, including locations in Michigan and Texas. To participate, individuals must complete a screening process and agree to follow all study procedures. Eligible participants will be randomly assigned to receive either investigational treatment or a placebo.
*All study-related procedures and treatments are provided at no cost. No insurance is required to participate, and eligible participants may receive compensation for time and travel.
Get Started
What to Expect?
If you are suffering from chronic heart failure and reduced kidney function, you may qualify for a paid clinical trial exploring new treatment options. After submitting the interest form above, a member of our research team will contact you for a brief pre-screening to determine if you meet the initial eligibility criteria.
If you qualify, you will be asked to review and sign an Informed Consent Form (ICF), which outlines all study procedures, potential benefits, and possible risks. Once consent is given, you will be invited to one of Revival’s research sites in Michigan or Texas for a screening visit. During this visit, we’ll review your medical history, conduct physical exams, and perform lab tests to confirm your eligibility. Participants who meet all study requirements will be enrolled in the Heart Failure & Kidney Failure Clinical Trial.
Our team is committed to ensuring you fully understand your role in the study and what to expect throughout. Please don’t hesitate to ask questions before making your decision. Your involvement helps advance future treatment options for heart and kidney.
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About Heart Failure & Impaired Kidney Function

Heart Failure
Heart Failure happens when the heart muscle becomes weak or stiff, making it difficult for the heart to pump blood around the body as well as it should. Blood carries oxygen to your muscles and organs. When they can’t get the oxygen, they need to work properly, some of the main symptoms of HF appear.
Impaired Kidney Function
Some medical conditions (like high blood pressure) and medications can put a strain on the kidneys making them work harder than normal. If the kidneys have been under strain or working too hard for too long, they can become damaged. As the kidneys become damaged, they are less able to function properly and do their many important jobs like:
- Removing waste and toxins from blood
- Stopping fluid building up in the body
- Helping to control blood pressure
- Helping to keep the bones healthy
Heart Failure & Kidney Failure May Be Caused By
- High blood pressure
- Coronary artery disease
- Diabetes
- Chronic inflammation
- Certain genetic and lifestyle factors
Common Symptoms Include
- Shortness of breath or fatigue
- Swelling in the legs, ankles, or feet
- Increased urination, especially at night
- Nausea, confusion, or poor appetite
- Muscle cramps and difficulty concentrating
Frequently Asked Questions
Your Guide to Heart Failure with Kidney Failure
Got questions about chronic heart failure and reduced kidney function? We’ve compiled answers to some of the most common questions about the condition including what causes it, how it’s treated, and what daily life with chronic heart failure and reduced kidney function can look like. Still can’t find what you’re looking for? Our team is here to help. Call us on +1 (248) 721-9539, and we’ll be happy to assist you.
What are the early warning signs of reduced kidney function in someone with CHF?
- Increased fatigue and weakness
- Alterations in urination patterns (increased frequency, urgency, presence of blood in urine)
- Loss of appetite or nausea
- Difficulty concentrating or confusion
What causes chronic heart failure and reduced kidney function?
Causes include conditions like coronary artery disease, hypertension, diabetes, and certain genetic factors. Lifestyle factors such as smoking and obesity can also increase the risk.
Can chronic heart failure and reduced kidney function improve with treatment?
Yes, with proper management, symptoms can often be reduced, and disease progression may be slowed. However, the extent of improvement depends on various factors, including the underlying cause, overall health, and adherence to treatment.
Are there any dietary changes I can make to manage both conditions?
Yes, a heart-healthy diet is crucial. This generally involves:
- Limiting salt intake to reduce fluid buildup (common in CHF) and workload on the kidneys.
- Choosing lean protein sources and limiting saturated fat to manage cholesterol and heart health.
- Focusing on fruits, vegetables, and whole grains for essential nutrients and fiber.
What is the cost of participating in a research study?
There’s no cost to participating in Heart Failure and Kidney Failure Clinical Trials, as the expenses are covered, including travel and participation costs.


