Struggling with Depression?
You Are Not Alone, Clinical Trials May Help
Major depressive disorder (MDD) is a medical condition that significantly affects an individual’s emotions and behavioral patterns. It can lead to persistent feelings of sadness, hopelessness, and a lack of interest in activities once enjoyed. Approximately around 8.3% individuals in the United States are affected by depression. Despite medical advancements, depression often goes undiagnosed or untreated due to stigma or limited access to care, underscoring the urgent need for more effective and accessible treatment options.
Living with MDD can interfere with work, relationships, sleep, appetite, and overall quality of life. In some cases, it may also increase the risk of other health issues such as heart disease, anxiety, or substance abuse. Timely intervention and support from loved ones can play a key role in managing symptoms and improving long-term outcomes.
If you or someone you know has major depressive disorder, psychiatrists at Revival Research Institute are conducting Depression Clinical Trials, exploring potential new treatment options.
Are You Eligible to Participate?
To qualify for the Depression Clinical Trials, participants must:
- Be male or female, 18 years or older
- Currently have a diagnosis of major depressive disorder
*Additional criteria may apply.
Participation in the Depression Clinical Trials is free of cost. To learn more or enroll, fill out the form below. A member of our research team will contact you to discuss your potential eligibility for the study.

About Major Depressive Disorder Clinical Trials
Living with major depressive disorder can significantly impact your daily life. Persistent sadness, lack of motivation, fatigue, and difficulty concentrating can interfere with work, relationships, sleep, and overall well-being.
Revival Research Institute is conducting a clinical trial for individuals suffering from major depressive disorder. This study is designed to evaluate the safety and efficacy of an investigational treatment that could potentially help people with their symptoms of depression.
Clinical trials will be conducted at multiple locations across the United States, including Texas. To qualify, participants must complete a screening process and comply with all study procedures. Those who meet eligibility criteria and are selected for the study will receive either investigational treatment or a placebo.
To take the next step, complete the form above. A member from our research team will contact you to determine if you qualify. A brief discussion about your health and medical history may be required.
*All study-related procedures and study treatments are provided at no cost. No insurance is required to participate, and eligible participants may receive compensation for time and travel.
Get Started
What to Expect?
If you are living with depression, you may qualify for a paid clinical trial exploring new treatment options. After completing the interest form above, a member of our research team will contact you for a brief pre-screening to determine if you meet the initial eligibility criteria.
If you qualify, you’ll be asked to review and sign an Informed Consent Form (ICF), which outlines all study procedures, potential benefits, and possible risks. Once consent is given, you will be invited to one of Revival’s research sites for a screening visit. During this visit, we will review your medical history, conduct physical exams, and perform lab tests to further assess your eligibility. If you meet all study requirements, you will be officially enrolled in the Major Depressive Disorder Clinical Trial.
Our team is committed to ensuring you fully understand your role in the study and what to expect throughout. Please feel free to ask any questions before deciding to participate. Your involvement helps advance future treatment options for major depressive disorder.
Age
18 years or older
Condition
Major Depressive Disorder
Location
Texas
Major Depressive Disorder: A Persistent Mental Health Challenge

Depression, also referred to as major depressive disorder or clinical depression, is a mood disturbance characterized by persistent feelings of despair and loss of interest. Though, this condition goes beyond temporary emotional lows. It affects how an individual feels, thinks, and behaves on a daily basis. People living with depression may experience emotional numbness, irritability, changes in appetite or sleep patterns, fatigue, difficulty concentrating, and a diminished ability to function in social, occupational, or personal settings.
Untreated depression can have profound consequences for both individuals and their families. The impact may impede every aspect of life, straining relationships, careers, and daily responsibilities. Complications may include substance abuse, anxiety disorder, panic disorders, social phobia, and even suicidal ideation.
Major Depressive Disorder May Be Triggered By
- Prolonged stress or traumatic events
- Relationship conflicts or social isolation
- Chronic illness or significant medical conditions
- Genetic predisposition or family history of depression
- Hormonal changes (e.g., postpartum or menopause)
- Substance abuse or withdrawal
Common Symptoms of Major Depressive Disorder Include
- Persistent sadness, hopelessness, or emptiness
- Loss of interest or pleasure in activities once enjoyed
- Fatigue or decreased energy
- Difficulty concentrating or making decisions
- Changes in appetite or weight
Frequently Asked Questions (FAQs)
Your Guide to Major Depressive Disorder
Got questions about Major Depressive Disorder? You’re not alone.
We’ve compiled answers to some of the most common questions about the condition—what causes it, how it’s treated, and what daily life with depression can look like. Still can’t find what you’re looking for? Our team is here to help. Reach out to us on +1 (248) 721-9539, and we’ll be happy to assist you.
What is major depressive disorder?
Major depressive disorder (MDD), commonly known as depression, is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a loss of interest or pleasure in activities. It affects how a person thinks, feels, and behaves, often leading to a variety of emotional and physical problems.
How is depression diagnosed?
The first step would be to consult your doctor. Some conditions and medications can mimic the symptoms of depression. Your doctor will rule out these conditions by running physical examinations, interview questions, and lab tests. Once the doctor confirms this is not due to a medical condition, they will either advise treatment options or refer to a mental health professional.
How is major depressive disorder different from feeling sad or having a bad day?
While everyone experiences sadness from time to time, MDD is a medical condition characterized by persistent low mood, loss of interest in daily activities, and other emotional and physical symptoms that last for at least two weeks or more. It affects daily functioning and often requires professional treatment to manage effectively.
What is the cost of participating in a research study?
There’s no cost to participating in our Depression Clinical Trials, as we cover all the expenses ourselves, including travel and participation costs.


