Skip to main content

Are you living with Heart Failure and Chronic Kidney Disease?

Participate in a Clinical Trial & be at the heart of potentially Life-changing Therapies.

There are effective drugs available in the market for people suffering from heart failure. However, these medications carry some major risks for people living with Heart Failure (HF) and kidneys with impaired function. Revival Research is conducting clinical trials on potential heart failure treatment that may help people living with HF and Chronic Kidney Disease (CKD).

You may be eligible to participate if you:

• Are at least 21 years of age or older
• Have HF with current or previous symptoms
• Have a decline in kidney function
• Are on diuretics (medications that help stop fluid build-up)

If you are interested in participating in the clinical trial or know someone who is, please feel free to get in touch with us by filling the form. Someone from the study team will call you to complete the screening process. Your well-being and health will be our main priority throughout the duration of the study.

*Participation in clinical trials is free of cost to you and your health insurance.
**Filling the form does not mean that you must join the study or that you will be able to participate.

Please provide YOUR contact information only.

About the Heart Failure Clinical Trials

The study is testing two study drugs, separately or combined to observe whether they are suitable for people who suffer from both Heart Failure and Chronic Kidney Disease.
We are doing this study to learn about how effective, tolerable, and safe the experimental drugs are in treating participants. An experimental drug means that it is not yet approved by any health authority including the FDA, except for use in research studies like this.

Participants who decide to take part in the study will help researchers and physicians understand this condition better. They will also play an active role in ongoing efforts to improve healthcare for other people. Participation in the Heart Failure clinical trials is completely voluntary, you can leave at any time. Leaving will not affect your care.

*Your participation in the research study is free of cost to both you and your private insurance. If you qualify and decide to participate in the study, you will be monetarily compensated for your time and travel.

Get Started: What to Expect?

During the visits to the study center, your health and response to the study drugs will be assessed through physical exams, collection of blood and urine samples. Participants may be asked to monitor their blood pressure or collect urine samples at home. At various points in the study, participants may also be asked to take back home certain devices to record data like daytime activities, heart rate, or sleep patterns. Participants will be asked to follow heart failure guidelines to maintain their heart health. The study doctor and the research staff will explain in detail everything that your participation entails in the Informed Consent Process if you decide to participate.

All assigned study drugs will be taken as capsules or tablets, by mouth with water, everyday in the morning. You will be required to record the time on a study diary. On the days when you are attending the study center visit, you will be given your assigned study drugs to take during the visit. You will have an equal chance of being assigned to the study treatment groups. Participants cannot choose which study drug(s) they receive; neither you nor the research staff will know which study drug you receive.

*Participants will receive study-related care from experienced study staff including doctors and nurses. Your health and well-being are our priority throughout the duration of the study.


Heart Failure

Length of Study Treatment

19 – 21 weeks (approx. 5 months)

Number of Study Visits

7 visits

About Heart Failure

Heart Failure Clinical trials

When the heart muscle doesn’t pump blood as well as it should, it causes heart failure, also known as congestive heart failure. When this happens, blood can back up in the lungs and fluid can build up, causing shortness of breath. Proper heart failure treatments in the elderly especially, can help them live longer by reducing the signs and symptoms of heart failure. Some of the most common heart failure guidelines include losing weight, exercising, limiting salt (sodium) in your diet, and managing stress are all examples of lifestyle changes that can enhance your quality of life.

Managing HF & Chronic Kidney Disease

Chronic HF continues to be a major cause of mortality, hospitalizations, and low quality of life. The prevalence of chronic HF continues to increase globally, especially in elderlies. When coupled with HF, Chronic Kidney Disease can worsen and vice versa. This results in worsening fluid retention and increased shortness of breath, edema, and electrolyte abnormalities. CKD & HF can sometimes be a complex, vicious cycle and is often difficult to treat. Management of HF usually involves medications and following heart failure guidelines that are unsuitable for people who suffer from chronic disease as well as heart failure. This is why there is an unmet medical need for heart failure treatments in the elderly that cater to chronic kidney failure as well. The best ways to manage HF and CKD include making dietary changes, reducing weight, and, exercising is known to improve quality of life and overall physical function.

Frequently Asked Questions

What is Cardiovascular Disease?

Cardiovascular disease is an umbrella term for conditions that affect your heart and the blood vessels. It most commonly occurs due to the build-up of fatty deposits that block the blood vessels around the heart.

What is the treatment for Congestive Heart Failure?

There is no treatment for heart failure. Many heart failure treatments aim to relieve the symptoms and the pain associated with heart failure. Doctors usually prescribe medications like diuretics, vasodilators, ACE Inhibitors, Beta-blockers and, anticoagulants. Although many of these drugs are effective, they carry risks that make them unsuitable for individuals with reduced kidney function.

How to prevent Cardiovascular Diseases?

Cardiovascular diseases or heart diseases can reduce one’s quality of life. Fortunately enough, there’s are things you can do to reduce the risks of the condition. This includes dietary changes, regular exercises, cutting down on sugary and fatty foods, limiting or stopping smoking and alcohol consumption, and managing your stress.

What causes Cardiovascular Disease?

Cardiovascular diseases are mainly caused by a blockage in the blood vessels that prevents blood from flowing to the heart. The most common reason for this is a build-up of fatty deposits on the inner walls of the blood vessels that supply the heart. However, other types of cardiovascular diseases may occur due to other reasons. Such as coronary artery disease, scarring of the heart muscle, genetic problems, or medications that can cause arrhythmias (the irregular rhythm of the heart).

Is the Heart Failure Clinical Trials location near me?

We match all our eligible participants to the closest site location. If we are not running the study in a 50-mile radius near you, we will save your details for later when the site of the study matches your location and is available.

Close Menu