Atopic Dermatitis Clinical Trials for Adolescent

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Living with Atopic Dermatitis?

Let Research Guide the Way to Relief

Atopic Dermatitis (AD) is a chronic inflammatory skin condition that affects millions worldwide. In the U.S. alone, studies show that up to 10% of adults and 14-24% of adolescents suffer from this condition. While many treatment options exist, not all patients respond effectively to current therapies, especially those with moderate disease and intense itching.

Revival Research Institute is now enrolling for clinical trial for atopic dermatitis in adults and adolescents. These studies are focused on testing investigational therapies aimed at managing symptoms like itching, redness, and inflammation.

To qualify for the clinical trial for atopic dermatitis adults and adolescents, participants must:

Be at least 12 years old at the time of consent
Have chronic atopic dermatitis for at least 1 year

*Additional Criteria may apply

Despite its prevalence, limited treatment options are available for patients, making clinical research crucial in finding effective therapies. Revival Research Institute is working to evaluate innovative treatment options for atopic dermatitis in adults & adolescents .

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About the Study: A Closer Look

This Phase 4 open-label clinical trial is designed specifically for a subset of patients with atopic dermatitis in adults and adolescents who experience limited body surface area involvement but significant itch burden.

Participants will receive a study drug, a monoclonal antibody targeting IL-13, which is believed to play a key role in AD inflammation and itching.

Eligible participants who enroll in the study will be asked to attend regular study visits, where they may undergo physical examinations, blood sample collection, and medical questionnaires. A team of experienced healthcare professionals will oversee your health and progress at every step. Participation in this clinical trial is completely voluntary.

*All study procedures and study-related treatments, including the investigational drug, are provided at no cost, and no insurance is required to participate.

*To take the next step, submit the form above, and our research staff will contact you to determine if you qualify for the study. A brief discussion about your health and medical history may be required.

Get Started: What to Expect?

Participation in this study may last up to 38 weeks, including a treatment period and a follow-up phase. This research is part of a Phase 4 open-label trial evaluating the safety and efficacy of lebrikizumab in treating atopic dermatitis in adults and adolescents. The study is open to individuals aged 12 years and older who meet specific eligibility criteria, including having moderate to severe AD with 10–25% body surface area involvement and a significant itch burden. Participants who qualify will receive study drug, administered via subcutaneous injection. The dosing schedule includes two initial doses followed by biweekly maintenance doses.

Throughout the study, a qualified research team will monitor participants’ health through regular site visits, physical exams, blood work, and symptom diaries.

Age

12 years+

Condition

Atopic Dermatitis

Location

Troy, MI & Evans, GA

Adults & Adolescents Atopic Dermatitis: A Burning & Itching Experience

Atopic Dermatitis (AD) is a chronic, relapsing skin condition marked by intense itching, redness, dryness, and inflammation. It frequently affects areas such as the face, neck, hands, inner elbows, and knees, although it can occur anywhere on the body. In moderate to severe cases, the itch-scratch cycle can lead to skin thickening, open sores, and infections. For many, this condition significantly affects quality of life, causing sleep disruption, emotional stress, and social withdrawal.

Skin barrier dysfunction and immune dysregulation are key contributors, with flares triggered by allergens, climate changes, and irritants. Many patients experience limited relief or treatment resistance, emphasizing the urgent need for newer therapeutic approaches. However, resistance to conventional treatments highlights the need for potential treatment options to improve patient outcomes

Frequently Asked Questions (FAQs)

What is atopic dermatitis, and how does it affect adults and adolescents?

Atopic dermatitis in adults and adolescents is a chronic skin condition marked by dry, itchy, and inflamed skin. It can interfere with sleep, school, work, and social activities due to the discomfort and appearance of skin lesions. The severity and triggers can vary by age group but often require long-term management.

What causes atopic dermatitis in adults and adolescents?

AD is caused by a combination of genetic, environmental, and immune system factors. Skin barrier dysfunction and an overactive immune response contribute to inflammation. Common triggers include allergens, irritants, stress, climate changes, and hormonal fluctuations during adolescence.

How is moderate to severe atopic dermatitis diagnosed in clinical trials?

Participants are usually diagnosed based on criteria such as Eczema Area and Severity Index (EASI), Investigator’s Global Assessment (IGA), and patient-reported itch severity using a Numerical Rating Scale (NRS). In this trial, eligibility includes 10–25% BSA involvement, an EASI score ≥16, IGA ≥3, and pruritus NRS ≥6.

Are there different treatment needs for adolescents compared to adults with AD?

Yes, adolescents may respond differently to treatments due to hormonal changes, body weight, and developing immune systems. That’s why clinical trials like this one evaluate safety and efficacy in both age groups to ensure appropriate treatment options are available for all.

Why should I consider joining a clinical trial for atopic dermatitis?

Clinical trials provide access to new investigational treatments not yet available to the public. Participants receive close medical supervision, study-related care at no cost, and contribute to the advancement of better therapies for people with atopic dermatitis.

Investigating New Therapies for Itch Relief and Skin Recovery