Prurigo Nodularis Clinical Trials

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Are you itching for relief from Prurigo Nodularis?

A Clinical Research Study may be an answer!

Prurigo Nodularis (PN) is a skin condition characterized by itchy rashes or nodules which appear on the arms and legs. While treating the PN itch can be difficult, research studies evaluating potential new treatments may be an option for you.

You may be eligible to participate in the research study if you:

Are above the age of 18 years
Have been diagnosed with Prurigo Nodularis
Have at least 20 nodules in 2 different areas of your body

We are conducting research studies on investigational oral medications that may be able to provide you with relief from the symptoms of PN.
To see if you or your loved ones qualify, please fill the form and someone from our research staff will give you a call.

*To participate in any of Revival Research Institute’s research studies, NO INSURANCE is required.
*If you are eligible for the research study, you may be compensated for your time and travel participating in the study.
*Qualified participants may receive an investigational product or placebo, and study-related medical evaluation, at no cost.

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About the Prurigo Nodularis (PN) Study

We are conducting clinical trials to observe the safety and efficacy of the study medications that may be able to help people suffering from chronic itch and bumps associated with PN. This study takes place at one of our sites in Troy, Michigan. Eligible participants may be asked to visit our site to complete the screening process.

Am I eligible to participate in the PN Study?

To be eligible for the study, at the time of volunteering, you need to:

Be over 18 years of age
Have at least 20 nodules, involving 2 different areas of your body
Have a diagnosis generalized Prurigo Nodularis

The study begins with a Screening Period during which your study doctor will gather your medical history and perform several examinations to determine if you are eligible to participate. Once the study doctor has determined that you are qualified to participate in this trial, your treatment option will be randomly selected by a computer at the second visit. This means that your treatment will be determined by chance, similar to tossing a coin. You will be randomly allocated to one of the two treatments:

Study drug, twice daily,
Placebo pills, twice daily.

*Investigational product or placebo, and study-related medical evaluation, will be provided to qualified participants at no cost. No insurance is required to participate.

Get Started: What to Expect?

Revival Research Institute is conducting a research study to gauge the safety and efficacy of an investigational medication that may help with your symptoms of PN. If you’re eligible for the research study, someone from our research staff will call you and invite you to our site for a visit. You may be compensated for your time and travel participating in the study.

The study doctor will go over all of the study requirements and the length of your participation in further detail during the screening process. To see if you’re a suitable fit for volunteering in our research trial you’ll be asked health-related questions. You will also be requested to sign an informed consent if you qualify upon screening and diagnostic tests.

Eligibility criteria are parameters that each clinical trial uses to determine who is eligible to participate. Age, sex, overall health, stage of disease, and personal treatment history are all aspects to consider. If you are willing to participate in a Clinical Research trial, you may be able to acquire free access to new experimental medicines and you will be compensated for any study-related care and procedure.

Get Started - See If You Qualify

About Prurigo Nodularis (PN)

PN is a skin condition in which hard, itchy nodules develop on the surface of the skin. Currently, there is no approved prurigo nodularis treatment specifically for itching associated with it. Therefore, understanding the condition and finding new treatment options for people with this condition is extremely important.

What Happens in PN?

Although it is known that scratching causes additional nodules to form, it is unclear what causes the irritation to begin with. Itchiness can be excruciating to the point where skin bleeds or hurt. Scratching aggressively can lead to the occurrence of additional skin lesions. The itching is highly bothersome and is associated with depression, sleep problems, and the lack of ability to do things that are enjoyed.

Common Symptoms of PN

The emergence of hard, irritating lumps on the skin is the predominant sign of PN. Previously irritated lesions may be covered by crusting and scaling. Lesions that are older may be darker or lighter than the surrounding skin.

Frequently Asked Questions

What is Prurigo Nodularis (PN)?

PN is a chronic inflammatory skin condition that causes irritating and itchy bumps or rash on the arms, legs, torso, or feet. It may cause burning, red and itchy bumps that could intensify over time.

How to get rid of Prurigo Nodularis?

There is an unmet need for prurigo nodularis treatment. Unfortunately, to date, there are no approved treatments. Topical treatments are used such as steroid creams, however, it has a more risk-to-benefit ratio, which means it could cause more harm than good for some people. However, researchers and doctors are trying to find a solution that may be able to treat pruritic skin conditions such as PN.

Is insurance required to volunteer?

Participating in clinical research trials at Revival Research Institute does not require any medical insurance.

What is the cause of Prurigo Nodularis?

There is no known cause for prurigo nodularis. However, it is more likely to form when the skin is irritated or scratched. It is thought that scratching the skin can cause nodules to break out on the skin. Many people who have PN usually have allergies or other skin conditions such as eczema.

Will I receive free treatment by participating in the research study?

Qualified participants may receive investigational product or placebo, and study related medical evaluation, at no cost. No insurance is required to participate in the research study. If you are eligible for the study, you may be compensated for your time and travel participating in the study.

Prurigo Nodularis