Skip to main content

Do you have Cardiovascular Disease & High Cholesterol Levels?

You might qualify for the Atherosclerotic Cardiovascular Disease Research Study!

Heart diseases including Atherosclerotic Cardiovascular Diseases are one of the leading causes of death for men and women in the United States. Despite advancements in medicine and treatments, there is still an unmet need for effective treatments that prevent and manage cardiovascular conditions. Lipoprotein(a) is also known as Lp(a). Lp(a) carries cholesterol (a type of fat) in the blood. If you have a high level of Lp(a), you may have a higher risk of heart disease, heart attack, or stroke.

Revival Research Institute is conducting a clinical research study evaluating the safety and effectiveness of an investigational drug in lowering Lp(a) in blood.

You may be eligible for the Clinical Research Study if you:

  • Are 55 years or older, and have certain risk factors for heart disease or stroke
  • Or are 18 years or older and already have heart disease or have had a stroke
  • Have a high level of Lipoprotein(a) in your blood

This Cardiovascular Disease Research Study will have Cardiologists and doctors gain a better understanding of the condition and observe whether the investigational medication helps lower “bad” cholesterol levels in the body that contribute to heart diseases.

*Participation in the Clinical Trial is completely free of cost and is your choice.

**To participate, fill out the form, and someone from our research staff will call you to see if you are eligible for the Clinical Research Study.

Please provide YOUR contact information only.
ASCVD Clinical Trials Flyer

About Atherosclerotic Cardiovascular Disease Research Study

Revival Research Institute, LLC is conducting a Cardiovascular Disease Research Study to observe the safety and effectiveness of a study drug that may be able to help lower Lp(a) and help people at risk for heart disease, including those with diabetes or kidney ailments, in hopes of creating a better future for heart health.

This clinical research study may be able to help people who have or are at risk for heart disease, stroke, or peripheral artery disease. The Cardiovascular Disease Research Study may last anywhere between 3.5 to 5 years. Participants can expect study visits with assessments including physical examination and blood tests. Every participant will be randomly assigned to one of two groups. One group with receive the placebo and the other group will receive the investigational drug.

*All study procedures and study-related treatment including the investigational drug is free of cost to you and insurance is not required to participate.

*The study doctor will take you through every step of the Clinical Trial before you decide to participate and will answer any questions you have about the study treatment.

What to Expect?

Once you agree to take part in the study, you will be asked to sign an Informed Consent Form that has all the details of the study. The study team will also be there to guide you about the process and your role in the study trials. We highly encourage all our participants to ask as many questions as they’d like before participating. In the end, the decision is all yours whether to take part or walk out of the trial.

Once the consent form is signed and all your questions are answered, you will be assigned to a group by random selection. The two groups in the Cardiovascular Disease Research Study are

  • Control group
  • Experimental group

The control group is given a placebo medication that does not have an active ingredient. In contrast, the experimental group is the one that is being treated with an actual study drug that has active ingredients. The study team is also unaware of the allocation as it is a double-blind research study, meaning neither the researcher nor the participant knows which treatment or intervention is being given to them.

In case of emergency or any mishap, the information about your study treatment will be revealed to the study doctor.


Atherosclerotic Cardiovascular Disease (ASCVD)

Length of Study

3.5 to 5 years

Number of Study Visits

Approx. 21 visits

About Atherosclerotic Cardiovascular Disease (ASCVD)

Atherosclerosis is the medical term for hardened and narrowed arteries due to cholesterol build-up. The hardening of these deposits over time causes Atherosclerotic Calcification. It is the leading cause of heart attacks, strokes, and Peripheral Vascular Disease (PAD). The alternate names for this condition are Arteriosclerosis and Atherosclerotic Cardiovascular Disease (ASCVD).

Atherosclerosis happens when the inner layer of the blood vessels called endothelium is damaged. It is responsible for keeping the arteries in shape and smooth in texture.

Some of the causes of ASCVD are:

  • High cholesterol levels
  • Smoking
  • High blood pressure
  • Diabetes
  • Inflammation

The symptoms of ASCVD include:

  • Unusual heartbeat
  • Pain in the chest, arms, jaw, and neck
  • Shortness of breath

Frequently Asked Questions

How long will the Cardiovascular Disease Research Study last?

The study will last between 3.5 to 5 years. The research study will include study visits including telephone and clinic visits.

What is the location of the Cardiovascular Disease Research Study?

Revival Research Institute is currently conducting the Cardiovascular Clinical Research Study in Michigan. If you are interested in participating in the research study, we will assign you to one of the nearest locations that may be within a 50-mile radius.

Will I receive the placebo or the actual study drug?

Since this is a double-blind, placebo-controlled study, you might be randomly assigned to either one of the two groups i.e. the group that receives the placebo or the control group that receives the investigational drug. You and your study doctor will not know which group you belong to or which medication you receive.

What causes Atherosclerotic Calcification?

Atherosclerosis occurs due to the narrowing of the arteries in the heart. This develops due to the buildup of plaque deposits composed of cholesterol and fat in the heart. Atherosclerotic calcification is the hardening of these deposits, especially in the bigger arteries of the heart.

Close Menu