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Chronic Kidney Disease and Cardiovascular Disease Clinical Trials

Advancing Cardiac and Kidney Care, One Clinical Trial at a Time
Cardiology

Struggling with Cardiac Issues Due to Kidney Dysfunction?

You might qualify for the Chronic Kidney Disease Research Study!

Kidneys play a crucial role in filtering toxins from the body, but kidney issues frequently lead to cardiovascular problems by disrupting fluid and electrolyte balance. This imbalance increases the risk of developing atherosclerotic cardiovascular disease, heart failure, and other conditions. Despite advancements in medicine and treatments, there remains an unmet need for effective interventions to prevent and manage cardiovascular complications associated with chronic kidney disease (CKD).

At Revival Research Institute, we are conducting chronic kidney disease and cardiovascular disease clinical trials evaluating the safety and effectiveness of an investigational drug in people with cardiovascular diseases and chronic kidney disease.

Could You Qualify for a CKD & Heart Health Study?

You may be eligible for the Cardiovascular and Chronic Kidney Disease Clinical Trials if you:

  • Are 45 years of age, or older
  • Have a BMI > 27.0 kg/m2
  • Have established atherosclerotic cardiovascular disease and/or chronic kidney disease diagnosis

*Additional criteria may apply.

This cardiovascular disease and chronic kidney disease clinical trial will observe whether the investigational medication helps manage the symptoms of chronic kidney disease that contribute to heart disease.

*Participation in the clinical trial is completely free of cost and voluntary.
**To participate, fill out the form below and someone from our research staff will call you to see if you are eligible for the clinical research study.

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Chronic Kidney Disease and Cardiovascular Disease Flyer

About Chronic Kidney Disease and Cardiovascular Disease Clinical Trial

Revival Research Institute is conducting Chronic Kidney Disease and Cardiovascular Disease Clinical Trials to observe the safety and effectiveness of a study drug that may be able to help people with chronic kidney disease and cardiovascular diseases. This includes people suffering mainly from atherosclerotic cardiovascular disease.

For cardiovascular disease and chronic kidney disease research, study participants can expect study visits with assessments including physical examination and blood tests. Every participant will be randomly assigned to one of two groups. One group with receive the placebo and the other group will receive the investigational drug.

By joining a CKD and Heart Disease Clinical Trial, you can help advance research that may lead to better treatments and brighter outcomes for the future.

*All study procedures and study-related treatments, including the investigational drug, are provided at no cost, and no insurance is required to participate. Participants may receive compensation for time and travel.

*To take the next step, submit the form above, and our research staff will contact you to determine if you qualify for the study. There may be a brief discussion about your health and medical history.

Get Started
What to Expect?

If you decide to take part in Chronic Kidney Disease and Cardiovascular Disease Clinical Trials, the first step will be signing an Informed Consent Form. This document contains detailed information about the study, including procedures, potential risks, and your rights as a participant.

If you qualify, you’ll be asked to review and sign an Informed Consent Form (ICF), which outlines all study procedures, potential benefits, and possible risks. Once consent is given, you will be invited to one of Revival’s research sites for a screening visit. During this visit, we will review your medical history, conduct physical exams, and perform lab tests to further assess your eligibility. If you meet all study requirements, you will be officially enrolled in the Chronic Kidney Disease and Cardiovascular Disease Clinical Trials

Our team is committed to ensuring you fully understand your role in the study and what to expect throughout the trial. Please feel free to ask any questions before deciding to participate. Your involvement helps advance future treatment options.

Get Started
Age Icon
Age
45 years or older
Condition Icon
Condition
Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease
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Location
Michigan & Texas

About Chronic Kidney Disease & Cardiovascular Issues

Chronic kidney disease (CKD) and cardiovascular issues are closely linked, with each condition accelerating the progression of the other. Chronic inflammation, oxidative stress, and the buildup of uremic toxins in people with CKD contribute to arterial stiffness and vascular calcification, which can lead to or worsen cardiovascular diseases such as heart failure and atherosclerosis. Therefore, managing both CKD and cardiovascular risk factors is essential to improving long-term outcomes and minimizing the risk of severe cardiovascular events in individuals with kidney disease.

Common Causes of Chronic Kidney Disease Include

  • Diabetes
  • Hypertension (High Blood Pressure)
  • Glomerulonephritis
  • Polycystic Kidney Disease (PKD)
  • Recurrent Kidney Infections
  • Long-term Use of Certain Medications

Symptoms of Chronic Kidney Disease

  • Fatigue or weakness
  • Swelling in the legs, ankles, or feet
  • Shortness of breath
  • Difficulty concentrating
  • Persistent itching
  • Changes in urination (frequency, color, or foaming)
  • Muscle cramps, especially at night
  • Nausea or vomiting
  • High blood pressure that’s difficult to control
  • Loss of appetite

Frequently Asked Questions

Questions about chronic kidney disease and cardiovascular disease?

We’ve compiled answers to some of the most common questions about the condition. Still can’t find what you’re looking for? Our team is here to help. Reach out to us on +1 (248) 721-9539, and we’ll be happy to assist you.

Chronic kidney disease and cardiovascular disease are closely linked. As kidney function declines, the risk of developing heart problems like heart failure, stroke, and heart attack increases. CKD can lead to high blood pressure, fluid overload, and abnormal calcium-phosphorus balance, all of which contribute to cardiovascular strain and damage.

Yes. Heart disease can impair kidney function, a condition known as cardiorenal syndrome. Reduced heart output lowers blood flow to the kidneys, decreasing their ability to filter waste. Over time, this can worsen kidney disease, especially in individuals with pre-existing CKD or high blood pressure.

CKD causes imbalances in electrolytes, hormones, and toxins, increasing the risk of atherosclerosis (hardening of the arteries). Anemia, inflammation, and fluid retention also put extra strain on the heart. These physiological changes elevate the risk of cardiac events even in the early stages of kidney disease.

Managing blood pressure, controlling blood sugar, maintaining a healthy weight, avoiding smoking, and following a heart-healthy, kidney-friendly diet (low in sodium, sugar, and processed foods) can significantly reduce the risk of both conditions. Regular exercise and medication adherence are also essential.

Revival Research Institute is currently conducting chronic kidney disease and cardiovascular disease clinical trials in Michigan. If you are interested in participating in the research study, we will assign you to one of the nearest locations that may be within a 50-mile radius.

Chronic kidney disease can arise from various factors, with some of the most common causes including hypertension (high blood pressure), diabetes mellitus, and obesity. Diabetes plays a significant role in chronic kidney disease development, as persistently elevated blood sugar levels can damage the kidneys’ filtering units over time. Additionally, obesity itself may directly impact kidney function through inflammatory processes and metabolic dysfunction.