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Struggling with Cardiac Issues Due to Kidney Dysfunction?

You might qualify for the Chronic Kidney Disease Research Study!

Kidneys play a crucial role in filtering toxins from the body, but kidney issues frequently lead to cardiovascular problems by disrupting fluid and electrolyte balance. This imbalance increases the risk of developing Atherosclerotic Cardiovascular Disease, Heart Failure, and other conditions. Despite advancements in medicine and treatments, there remains an unmet need for effective interventions to prevent and manage cardiovascular complications associated with chronic kidney disease.

At Revival Research Institute, we are conducting Chronic Kidney Disease and Cardiovascular Disease Clinical Trials evaluating the safety and effectiveness of an investigational drug in people with cardiovascular diseases and chronic kidney disease.

You may be eligible for the Cardiovascular and Chronic Kidney Disease Clinical Trials if you:

  • 45 years of age, or older
  • Have a BMI >27.0 kg/m2
  • Have established Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease diagnosis

*Additional criteria may apply

This Cardiovascular Disease and Chronic Kidney Disease Clinical Trial will observe whether the investigational medication helps manage the symptoms of chronic kidney disease that contribute to heart diseases.

*Participation in the clinical trial is completely free of cost and voluntary.
**To participate, fill out the form and someone from our research staff will call you to see if you are eligible for the clinical research study.

Please provide YOUR contact information only.

About Chronic Kidney Disease and Cardiovascular Disease Clinical Trial

Revival Research Institute is conducting Chronic Kidney Disease and Cardiovascular Disease Clinical Trials to observe the safety and effectiveness of a study drug that may be able to help people with chronic kidney disease and cardiovascular diseases. This includes people suffering mainly from Atherosclerotic Cardiovascular Disease.

For Cardiovascular Disease and Chronic Kidney Disease Research, study participants can expect study visits with assessments including physical examination and blood tests. Every participant will be randomly assigned to one of two groups. One group with receive the placebo and the other group will receive the investigational drug.

*All study procedures and study-related treatment including the investigational drug is free of cost to you and insurance is not required to participate.
*The study doctor will take you through every step of the clinical trial before you decide to participate and will answer any questions you have about the study treatment.

Get Started: What to Expect?

Once you agree to take part in the Chronic Kidney Disease and Cardiovascular Disease Clinical Trials, you will be asked to sign an Informed Consent Form that has all the details of the study. The study team will also be there to guide you about the process and your role in the study trial. We highly encourage all our participants to ask as many questions as they’d like, before participation. In the end, the decision is all yours whether to take part or walk out of the trial.

Once the consent form is signed and all your questions are answered, you will be assigned to a group by random selection. The two groups in the Cardiovascular Disease and Chronic Kidney Disease Research Study are:

  • Control group
  • Experimental group

The control group is given a placebo medication that does not have an active ingredient of the medicine, whereas the experimental group is the one that is being treated with an actual study drug that has active ingredients. The study team is also unaware of the allocation as it is a double-blind research study, meaning neither the researcher nor the participant knows which treatment or intervention is being given to them.

In case of an emergency, the information about your study treatment at the Chronic Kidney Disease and Cardiovascular Disease Clinical Trials will be revealed to your study doctor.


Atherosclerotic Cardiovascular Disease (ASCVD)

Length of Study

3 to 4 years

No. of Study Visits:

8 to 9 visits

About Chronic Kidney Disease & Cardiovascular Issues

Chronic kidney disease (CKD) and cardiovascular issues are interconnected, each condition elevating the other’s progression. Chronic inflammation, oxidative stress, and the accumulation of uremic toxins in chronic kidney disease patients contribute to arterial stiffness, and vascular calcification, all of which promote cardiovascular disease progression. Thus, managing both CKD and cardiovascular risk factors is crucial for improving outcomes and reducing the risk of adverse cardiovascular events in patients with kidney disease.

Some of the causes of chronic kidney disease are:

  • Diabetes
  • Hypertension (High Blood Pressure)
  • Glomerulonephritis
  • Polycystic Kidney Disease (PKD)
  • Recurrent Kidney Infections
  • Long-term Use of Certain Medications

Frequently Asked Questions

What is the location of the Cardiovascular Disease and Chronic Kidney Disease Research Study?

Revival Research Institute is currently conducting Chronic Kidney Disease and Cardiovascular Disease Clinical Trials in Michigan. If you are interested in participating in the research study, we will assign you to one of the nearest locations that may be within a 50-mile radius.

Will I receive the placebo or the actual study drug?

Since this is a double-blind, placebo-controlled study, you might be randomly assigned to either one of the two groups i.e. the group that receives the placebo or the control group that receives the investigational drug. You and your study doctor will not know which group you belong to or which medication you receive.

What causes Chronic Kidney Disease?

Chronic kidney disease can arise from various factors, with some of the most common causes including hypertension (high blood pressure), diabetes mellitus and obesity. Diabetes plays a significant role in chronic kidney disease development, as persistently elevated blood sugar levels can damage the kidneys’ filtering units over time. Additionally, obesity itself may directly impact kidney function through inflammatory processes and metabolic dysfunction.

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