When Breathing & Beating Get Tough
Participate in Pulmonary Hypertension & Heart Failure Clinical Trials!
Pulmonary hypertension and heart failure are serious cardiovascular conditions that significantly affect heart and lung function. Pulmonary hypertension occurs when the blood pressure in the arteries of the lungs becomes dangerously high, while heart failure refers to the heart’s inability to pump blood effectively. Both conditions can lead to fatigue, shortness of breath, swelling, and a reduced quality of life.
These diseases may develop due to a variety of underlying causes, including chronic lung disease, heart valve problems, or other cardiovascular complications. Over time, they can strain the body’s ability to function normally, both physically and emotionally.
If you or someone you know is living with pulmonary hypertension and heart failure, Revival Research Institute is currently conducting clinical trials to explore potential new treatment options aimed at improving outcomes and quality of life.
Is this Clinical Trial the Right Fit for You?
The eligibility criteria to participate in the Heart Failure and Pulmonary Hypertension Clinical Trials includes:
- Being a male or female between the ages of 18 to 85 years
- Having a diagnosis of heart failure
- Having pulmonary hypertension due to heart failure with preserved ejection fraction (PH-HFpEF)
*Additional criteria may apply.
Participation in the Pulmonary Hypertension and Heart Failure Clinical Trials is completely free. To learn more or see if you qualify, simply fill out the form below. A member of our research team will reach out to discuss your eligibility and guide you through the next steps.
Pulmonary Hypertension and Heart Failure Clinical Trials
Living with pulmonary hypertension and heart failure can significantly impact your daily life, causing shortness of breath, fatigue, chest discomfort, and reduced ability to carry out everyday activities. These conditions can affect both physical and emotional well-being, making treatment and support essential.
Revival Research Institute is currently conducting a clinical trial to evaluate the safety and effectiveness of an investigational treatment for individuals diagnosed with pulmonary hypertension and heart failure. The goal of this study is to explore whether the treatment can improve heart and lung function, energy levels, and overall quality of life.
The trial is being conducted at multiple research sites across the United States, including locations in Texas. To participate, individuals will go through a screening process and must be willing to follow all study-related procedures. Eligible participants will be randomly assigned to receive either the investigational treatment or a placebo.
*All study-related care, procedures, and medication are provided at no cost. No insurance is required to participate, and eligible participants may also be compensated for their time and travel.
Get Started
What to Expect?
If you’re living with pulmonary hypertension and heart failure, you may qualify for a paid clinical trial exploring new investigational treatment options. After submitting the interest form above, a member of our research team will contact you for a brief pre-screening to determine if you meet the initial eligibility criteria.
If you qualify, you’ll be asked to review and sign an Informed Consent Form (ICF), which outlines all study procedures, potential benefits, and possible risks. Once consent is provided, you will be invited to one of Revival’s sites in Texas for a screening visit. During this visit, we’ll go over your medical history, conduct physical exams, and perform lab tests to confirm eligibility. Participants who meet all study requirements will be enrolled in the Pulmonary Hypertension and Heart Failure Clinical Trial.
Our team is dedicated to making sure you fully understand your role in the study and what to expect at each step. Feel free to ask questions at any time. Your participation plays an important role in helping us advance future treatment options for these serious and complex cardiovascular conditions.
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Understanding Pulmonary Hypertension and Heart Failure

Pulmonary hypertension and heart failure are serious cardiovascular conditions that often coexist and significantly impact overall health. Pulmonary hypertension occurs when the blood pressure in the lungs’ arteries is abnormally high, making it harder for the heart to pump blood through the lungs. Heart failure develops when the heart can’t pump enough blood to meet the body’s needs, leading to fatigue, shortness of breath, and fluid buildup.
Pulmonary hypertension and heart failure can severely affect exercise capacity, oxygen delivery, and energy levels. Without timely treatment, they can lead to complications such as arrhythmias, organ dysfunction, and reduced quality of life.
Pulmonary Hypertension and Heart Failure May Be Caused By
- Congenital heart defects
- Chronic lung disease (e.g., COPD)
- Left heart disease
- Pulmonary embolism (blood clots in the lungs)
- Connective tissue disorders (e.g., scleroderma)
Common Symptoms of Pulmonary Hypertension and Heart Failure
- Shortness of breath, especially during activity or when lying down
- Fatigue or weakness
- Swelling in the legs, ankles, or abdomen (edema)
- Chest pain or discomfort
- Rapid or irregular heartbeat (palpitations)
Frequently Asked Questions
Your Guide to Pulmonary Hypertension & Heart Failure
Got questions about Pulmonary Hypertension and Heart Failure?
We’ve compiled answers to some of the most common questions about these conditions, what causes them, how they’re treated, and what daily life with pulmonary hypertension and heart failure can look like. Still can’t find what you’re looking for? Our team is here to help. Call us at +1 (248) 721-9539, and we’ll be happy to assist you.
What is the treatment for heart failure and pulmonary hypertension?
There is no treatment for heart failure and pulmonary hypertension. The available treatment may only improve symptoms and prevent the disease from getting worse. This is why it is a good idea to participate in Heart Failure and Pulmonary Hypertension Clinical Trials. Participating in clinical trials may provide you with options and access to novel therapies that may otherwise not be available in the market.
Who is at risk of pulmonary hypertension?
Pulmonary hypertension occurs mostly between the ages of 30 and 60. There are some factors that contribute to the development of this condition. These are:
- Previous family history of the disease
- Being overweight
- Smoking
- Having blood clotting disorders
- Congenital heart disease
Who can participate in heart failure and pulmonary hypertension clinical trials?
For this study, the participants should have pulmonary hypertension with heart failure and preserved ejection fraction. If your hemodynamics are of the qualifying range, as verified by a right heart catheterization (RHC), and you meet the participation criteria, you may be able to join!
How is pulmonary hypertension related to heart failure?
Over time, the strain caused by pulmonary hypertension can weaken the right side of the heart, leading to right heart failure. Additionally, left heart failure (especially in heart failure with preserved or reduced ejection fraction) can also cause pulmonary hypertension.


