Heart Failure & Pulmonary Hypertension Clinical Trials

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Preserving Heart Health

Enroll in Heart Failure & Pulmonary Hypertension Clinical Trials in Sherman, Texas!

Heart failure (HF) with preserved ejection fraction (HFpEF) is the most frequently occurring subtype of heart failure (WHO Class 2) and it comprises up to 50% of all heart failure cases. Elevated left atrial pressure can cause congestion in the pulmonary veins, which can lead to increased pulmonary pressure (or pulmonary hypertension) and right ventricular (RV) failure. This can result in low cardiac output, edema, hypoxemia, and severely limited exercise capacity.

Revival Research Institute is conducting heart failure and pulmonary hypertension clinical trials in Sherman, Texas. This clinical trial aims to study the safety and efficacy of an investigational therapy, that could potentially change the way pulmonary hypertension with heart failure is managed.

The eligibility criteria to participate in the heart failure and pulmonary hypertension clinical trials in Sherman, Texas:

Males and females 18 to 85 years of age
Diagnosed with heart failure
Have pulmonary hypertension due to heart failure with preserved ejection fraction (PH-HFpEF)

*Additional criteria may apply
*If you are interested in participating in the clinical trial or know someone who is, please feel free to get in touch with us by filling out the form. Someone from the study team will call you to complete the screening process. Your well-being and health will be our main priority throughout the duration of the study.
**Participation in clinical trials is free of cost to you and your health insurance.
***Filling the form does not mean that you must join the study or that you will be able to participate.

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About Heart Failure & Pulmonary Hypertension Clinical Trials in Sherman, Texas

Revival Research Institute is conducting a phase 3, double-blind, placebo-controlled study that may last up to 104 weeks. The goal of the heart failure and pulmonary hypertension clinical trials in Sherman, Texas is to observe whether the study drug can help people with pulmonary hypertension with heart failure with preserved left ventricular ejection fraction (PH-HFpEF).

We are doing this study to learn about how effective, tolerable, and safe the investigational drugs are in treating participants. An investigational or experimental drug means that it is not yet approved by any health authority including the FDA, except for use in research studies like this.

Participants who decide to take part in the study will help researchers and physicians understand this condition better. They will also play an active role in ongoing efforts to improve healthcare for other people. Participation in the heart failure and pulmonary hypertension clinical trials in Sherman, Texas is completely voluntary, you can leave at any time. Leaving the study will not affect your care.
*Your participation in the research study is free of cost to both you and your private insurance. If you qualify and decide to participate in the study, you will be monetarily compensated for your time and travel.

Get Started: What to Expect?

If you meet the study criteria for the heart failure and pulmonary hypertension clinical trials in Sherman, Texas, you will be randomly assigned to one of the two groups. Participants will either receive the study drug, or a placebo for 12 weeks followed by 2 weeks of follow-up. After completion of this initial phase, participants will have the option to partake in an open-label extension that could continue for 104 weeks.

After you fill out the form above, someone from our research team will give you a call. If you fit the heart failure and pulmonary hypertension clinical trial’s eligibility criteria, you might be invited to the study site’s location (within a 50-mile radius). Before you decide to participate, our study team will brief you on all details about participating in the clinical trial, including the risks and benefits. Throughout the study, the research team will monitor your condition and look out for any adverse or severely adverse effects.

*Participants will receive study-related care from experienced study staff including doctors and nurses. Your health and well-being are our priority throughout the duration of the study.

Condition

Pulmonary Hypertension with Heart Failure

Length of Study

12 weeks

No. of Study Visits:

Approx. 6 visits

The Heartbreaking Duo: Pulmonary Hypertension & Heart Failure

Heart Failure & Pulmonary Hypertension Clinical Trials

In pulmonary arterial hypertension, the blood vessels supplying blood to the lungs become narrow and stiff. This reduces blood going into the lungs. To compensate for the lack of blood supply to the lungs, the heart starts to work harder to pump blood. This results in an increase in the size of the right ventricle of the heart.

Over time, the heart muscle becomes weak and fails to carry out its necessary function resulting in symptoms like fatigue, shortness of breath, dizziness, and severe exercise limitation making walking difficult. When the heart pumps blood with preserved ejection fraction (amount of blood pumped in each heart contraction) it is known as Heart failure (HF) with preserved ejection fraction (HFpEF).

The Revival team is dedicated to conducting heart failure and pulmonary hypertension clinical trials in Sherman, Texas, that would possibly help people manage their condition.

Frequently Asked Questions

What is the treatment for heart failure and pulmonary hypertension?

There is no treatment for heart failure and pulmonary hypertension. The available treatment may only improve symptoms and prevent the disease from getting worse. This is why it is a good idea to participate in heart failure and pulmonary hypertension clinical trials in Sherman, Texas. Participating in clinical trials may provide you with options and access to novel therapies that may otherwise not be available in the market.

Who is at risk of pulmonary hypertension?

Pulmonary hypertension occurs mostly between the ages of 30 and 60. There are some factors that contribute to the development of this condition. These are:

Previous family history of the disease
Being overweight
Smoking
Having blood clotting disorders
Congenital heart disease

If you have pulmonary hypertension with heart failure, we invite you to join our heart failure and pulmonary hypertension clinical trials in Sherman, Texas.

Who can participate in heart failure and pulmonary hypertension clinical trials in Sherman, Texas?

For this study, the participants should have pulmonary hypertension with heart failure and preserved ejection fraction. If your hemodynamics are of the qualifying range, as verified by a right heart catheterization (RHC), and you meet the participation criteria, you may be able to join!

Where are the heart failure and pulmonary hypertension clinical trials being carried out?

Currently, we are carrying out heart failure and pulmonary hypertension clinical trials in Sherman, Texas. We match all our eligible participants to the closest site location. If we are not running the study in a 50-mile radius near you, we will save your details for later when the site of the study matches your location and is available.