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A Potential Breakthrough in Heart Health

Heart Failure Clinical Trials in Michigan Are Now Enrolling!

Heart failure is a complex clinical syndrome causing structural or functional impairment of ventricular filling or emptying, leading to the heart’s inability to meet the body’s oxygenated blood needs. It does not literally mean the heart has failed but rather that it is not pumping blood as well as it should.

Revival Research Institute is conducting heart failure clinical trials in Michigan. This clinical trial aims to study the safety and efficacy of an investigational therapy for heart failure, that could potentially change the way heart failure is managed.

Eligibility criteria for heart failure clinical trials in Michigan:

  • Males and females above 18 years
  • Diagnosed with heart failure
  • Currently receiving ACE inhibitors, ARBs, or ARNIs

If you are interested in participating in the clinical trial or know someone who is, please feel free to get in touch with us by filling out the form. Someone from the study team will call you to complete the screening process. Your well-being and health will be our main priority throughout the duration of the study.

*Participation in clinical trials is free of cost to you and your health insurance.
**Filling the form does not mean that you must join the study or that you will be able to participate.

Please provide YOUR contact information only.

About the Heart Failure Clinical Trials in Michigan

Revival Research Institute is conducting a Phase 2 clinical trial that may last up to 24 weeks. The goal of the heart failure clinical trials in Michigan is to observe whether the subcutaneous injections of this drug can help manage heart failure symptoms and improve the condition.

We are doing this study to learn about how effective, tolerable, and safe the experimental drugs are in treating participants. An experimental drug means that it is not yet approved by any health authority including the FDA, except for use in research studies like this.

Participants who decide to take part in the study will help researchers and physicians understand this condition better. They will also play an active role in ongoing efforts to improve healthcare for other people. Participation in the heart failure clinical trials in Michigan is completely voluntary, you can leave at any time. Leaving the study will not affect your care.

*Your participation in the research study is free of cost to both you and your private insurance. If you qualify and decide to participate in the study, you will be monetarily compensated for your time and travel.

Get Started: What to Expect?

If you meet the study criteria for the heart failure clinical trials in Michigan, you will be randomly assigned to separate groups. Participants randomized to the study drug group, or its matching placebo will receive 1 subcutaneous injection every 4 weeks, with a total of 4 injections during the 16-week treatment period. Other participants randomized to sacubitril/valsartan will receive it for 16 weeks as well.

After you fill out the form above, someone from our research team will give you a call. If you fit the heart failure clinical trials in Michigan eligibility criteria, you might be invited to the study site’s location (within a 50-mile radius). Before you decide to participate, our study team will brief you on all details about participating in the clinical trial, including the risks and benefits. Throughout the study, the research team will monitor your condition and look out for any adverse or severely adverse effects.

*Participants will receive study-related care from experienced study staff including doctors and nurses. Your health and well-being are our priority throughout the duration of the study.


Heart Failure

Length of Study

24 weeks

Number of Study Visits

Approx. 8 on-site visits

What Is Heart Failure & Why Is It Such A Big Deal?

Heart failure (or HF) is a global public health issue causing frequent hospitalizations and a compromised quality of life. In the United States, HF affects more than six million individuals, which is approximately 1.8% of the total population.

This complex clinical syndrome results in structural or functional impairment of ventricular filling or emptying, leading to the heart’s inability to meet the body’s need for oxygenated blood. The natural course involves symptom deterioration, repeated hospitalizations, and more due to arrhythmia or progressive pump failure.

The Revival team is dedicated to conducting heart failure clinical trials in Michigan, aiming to alleviate the burden of HF and offer hope to those affected.

Frequently Asked Questions

What is Cardiovascular Disease?

Cardiovascular disease is an umbrella term for conditions that affect your heart and blood vessels. It most commonly occurs due to the build-up of fatty deposits that block the blood vessels around the heart.

What is the treatment for Congestive Heart Failure?

There is no treatment for heart failure. Many heart failure treatments aim to relieve the symptoms and the pain associated with heart failure. Doctors usually prescribe medications like diuretics, vasodilators, ACE Inhibitors, Beta-blockers and anticoagulants. Although many of these drugs are effective, they carry risks that make them unsuitable for individuals with reduced kidney function.

How to prevent Cardiovascular Diseases?

Cardiovascular diseases or heart diseases can reduce one’s quality of life. Fortunately enough, there are things you can do to reduce the risks of the condition. This includes dietary changes, regular exercises, cutting down on sugary and fatty foods, limiting or stopping smoking and alcohol consumption, and managing your stress.

What causes Cardiovascular Disease?

Cardiovascular diseases are mainly caused by a blockage in the blood vessels that prevents blood from flowing to the heart. The most common reason for this is a build-up of fatty deposits on the inner walls of the blood vessels that supply the heart. However, other types of cardiovascular diseases may occur due to other reasons. Such as coronary artery disease, scarring of the heart muscle, genetic problems, or medications that can cause arrhythmias (the irregular rhythm of the heart).

Are the Heart Failure Clinical Trials in Michigan near me?

We match all our eligible participants to the closest site location. If we are not running the study in a 50-mile radius near you, we will save your details for later when the site of the study matches your location and is available.

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